Forum Discussion
Loadbalance SMTP relay on F5 and exchange 2010 (Urgent help needed)
Disabling SNAT means that your hub transport servers would see the communications as if they were coming from the actual client IP addresses. Hub server response traffic to the clients would need to return through the F5 in order for the connections to work. Otherwise, the client would see return traffic from a different IP address and the connections would never establish. You'd need some type of policy based routing if the LTM isn't directly in the communications path.
Regarding the custom connector you mention, is that a separate IP address on the hub transport server or are both listening on the same IP address?
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