iRule Not working SIMPLE AND URGENT

As I always recommend, add some log statements to find out where your logic is going bad.

when HTTP_REQUEST {
  log local0. "Host: [HTTP::host]
  log local0. "Uri: [HTTP::uri]"
  if {[HTTP::host] contains "206.112.74.148"}{
    log local0. "Host contains 206.112.74.148"
    if {[HTTP::uri] ends_with ".jpg"}{
      log local0. "uri ends with .jpg"
      node 10.1.0.50 80
    } else {
      log local0. "uri doesn't end with .jpg"
      pool iwrewards
    }
  }
}

run your test traffic through the virtual and then look at the /var/log/ltm file. This should point out any changes you need to make to get your logic working correctly.

And, once you have everything working, remove the log statements before you put this into production.

-Joe