I rule

In my scenario we are planning to have a WILDCARD VIP for laodbalacning services 443 , 5222 & 5223 so if i create a simple TCP profile and use this Irule mentioed above would it work

yes.

this is another example using switch.

 configuration

root@(ve11c)(cfg-sync In Sync)(Active)(/Common)(tmos) list ltm virtual bar
ltm virtual bar {
    destination 172.28.24.10:0
    ip-protocol tcp
    mask 255.255.255.255
    profiles {
        tcp { }
    }
    rules {
        qux
    }
    source 0.0.0.0/0
    source-address-translation {
        type automap
    }
    vs-index 8
}
root@(ve11c)(cfg-sync In Sync)(Active)(/Common)(tmos) list ltm pool foo*
ltm pool foo {
    members {
        200.200.200.101:80 {
            address 200.200.200.101
        }
    }
}
ltm pool foo443 {
    members {
        200.200.200.101:443 {
            address 200.200.200.101
        }
    }
}
ltm pool foo5222 {
    members {
        200.200.200.101:5222 {
            address 200.200.200.101
        }
    }
}
ltm pool foo5223 {
    members {
        200.200.200.101:5223 {
            address 200.200.200.101
        }
    }
}
root@(ve11c)(cfg-sync In Sync)(Active)(/Common)(tmos) list ltm rule qux
ltm rule qux {
    when CLIENT_ACCEPTED {
  switch [TCP::local_port] {
    443 { pool foo443 }
    5222 { pool foo5222 }
    5223 { pool foo5223 }
    default {
       Do something
    }
  }
}
when SERVER_CONNECTED {
  log local0. "clientside client=[IP::client_addr]:[TCP::client_port] \
    clientside server=[clientside {IP::local_addr}][clientside {TCP::local_port}] \
    serverside client=[IP::local_addr]:[TCP::local_port] \
    serverside server=[IP::server_addr]:[TCP::server_port] \
    pool=[LB::server pool]"
}
}

 /var/log/ltm

[root@ve11c:Active:In Sync] config  tail -f /var/log/ltm
Mar  9 19:02:05 ve11c info tmm[15262]: Rule /Common/qux : clientside client=192.168.206.73:50589  clientside server=172.28.24.10443  serverside client=200.200.200.14:50589  serverside server=200.200.200.101:443  pool=/Common/foo443
Mar  9 19:02:18 ve11c info tmm1[15262]: Rule /Common/qux : clientside client=192.168.206.73:50595  clientside server=172.28.24.105222  serverside client=200.200.200.14:50595  serverside server=200.200.200.101:5222  pool=/Common/foo5222
Mar  9 19:02:38 ve11c info tmm1[15262]: Rule /Common/qux : clientside client=192.168.206.73:50606  clientside server=172.28.24.105223  serverside client=200.200.200.14:50606  serverside server=200.200.200.101:5223  pool=/Common/foo5223