How we can publish multiple applications/URLs on same VIP & redirect traffic to Same application server , but to different ports based on host header ?

Hello,

Best option to achieve your requirement would be use of LTM policy as given in above post. You can also achieve same using iRule as given below.

when HTTP_REQUEST 
 
{
 
  switch [HTTP::host] {
 
"xyz.com" {pool App01-9000}
 "abc.com" {pool App01-9010}
 
 }
 
 }

Hope it helps!

Mayur