how to remove Cipher from SSL profile

Just use the exclamation mark to exclude a cipher suite you don't want, and append it to your cipher config. Assuming that you have no other cipher customization in place at this point, the end result would be

DEFAULT:!ECDHE-RSA-AES256-SHA384

 tmm --clientciphers 'DEFAULT'
       ID  SUITE                            BITS PROT    METHOD  CIPHER  MAC     KEYX
 0:    61  AES256-SHA256                    256  TLS1.2  Native  AES     SHA256  RSA
 1:    53  AES256-SHA                       256  TLS1    Native  AES     SHA     RSA
 2:    53  AES256-SHA                       256  TLS1.1  Native  AES     SHA     RSA
 3:    53  AES256-SHA                       256  TLS1.2  Native  AES     SHA     RSA
 4:    53  AES256-SHA                       256  DTLS1   Native  AES     SHA     RSA
 5:    60  AES128-SHA256                    128  TLS1.2  Native  AES     SHA256  RSA
 6:    47  AES128-SHA                       128  TLS1    Native  AES     SHA     RSA
 7:    47  AES128-SHA                       128  TLS1.1  Native  AES     SHA     RSA
 8:    47  AES128-SHA                       128  TLS1.2  Native  AES     SHA     RSA
 9:    47  AES128-SHA                       128  DTLS1   Native  AES     SHA     RSA
10:    10  DES-CBC3-SHA                     192  TLS1    Native  DES     SHA     RSA
11:    10  DES-CBC3-SHA                     192  TLS1.1  Native  DES     SHA     RSA
12:    10  DES-CBC3-SHA                     192  TLS1.2  Native  DES     SHA     RSA
13:    10  DES-CBC3-SHA                     192  DTLS1   Native  DES     SHA     RSA
14:     5  RC4-SHA                          128  TLS1    Native  RC4     SHA     RSA
15:     5  RC4-SHA                          128  TLS1.1  Native  RC4     SHA     RSA
16:     5  RC4-SHA                          128  TLS1.2  Native  RC4     SHA     RSA
17: 49192  ECDHE-RSA-AES256-SHA384          256  TLS1.2  Native  AES     SHA384  ECDHE_RSA
18: 49172  ECDHE-RSA-AES256-CBC-SHA         256  TLS1    Native  AES     SHA     ECDHE_RSA
19: 49172  ECDHE-RSA-AES256-CBC-SHA         256  TLS1.1  Native  AES     SHA     ECDHE_RSA
20: 49172  ECDHE-RSA-AES256-CBC-SHA         256  TLS1.2  Native  AES     SHA     ECDHE_RSA
21: 49191  ECDHE-RSA-AES128-SHA256          128  TLS1.2  Native  AES     SHA256  ECDHE_RSA
22: 49171  ECDHE-RSA-AES128-CBC-SHA         128  TLS1    Native  AES     SHA     ECDHE_RSA
23: 49171  ECDHE-RSA-AES128-CBC-SHA         128  TLS1.1  Native  AES     SHA     ECDHE_RSA
24: 49171  ECDHE-RSA-AES128-CBC-SHA         128  TLS1.2  Native  AES     SHA     ECDHE_RSA
25: 49170  ECDHE-RSA-DES-CBC3-SHA           192  TLS1    Native  DES     SHA     ECDHE_RSA
26: 49170  ECDHE-RSA-DES-CBC3-SHA           192  TLS1.1  Native  DES     SHA     ECDHE_RSA
27: 49170  ECDHE-RSA-DES-CBC3-SHA           192  TLS1.2  Native  DES     SHA     ECDHE_RSA

tmm --clientciphers 'DEFAULT:!ECDHE-RSA-AES256-SHA384'
       ID  SUITE                            BITS PROT    METHOD  CIPHER  MAC     KEYX
 0:    61  AES256-SHA256                    256  TLS1.2  Native  AES     SHA256  RSA
 1:    53  AES256-SHA                       256  TLS1    Native  AES     SHA     RSA
 2:    53  AES256-SHA                       256  TLS1.1  Native  AES     SHA     RSA
 3:    53  AES256-SHA                       256  TLS1.2  Native  AES     SHA     RSA
 4:    53  AES256-SHA                       256  DTLS1   Native  AES     SHA     RSA
 5:    60  AES128-SHA256                    128  TLS1.2  Native  AES     SHA256  RSA
 6:    47  AES128-SHA                       128  TLS1    Native  AES     SHA     RSA
 7:    47  AES128-SHA                       128  TLS1.1  Native  AES     SHA     RSA
 8:    47  AES128-SHA                       128  TLS1.2  Native  AES     SHA     RSA
 9:    47  AES128-SHA                       128  DTLS1   Native  AES     SHA     RSA
10:    10  DES-CBC3-SHA                     192  TLS1    Native  DES     SHA     RSA
11:    10  DES-CBC3-SHA                     192  TLS1.1  Native  DES     SHA     RSA
12:    10  DES-CBC3-SHA                     192  TLS1.2  Native  DES     SHA     RSA
13:    10  DES-CBC3-SHA                     192  DTLS1   Native  DES     SHA     RSA
14:     5  RC4-SHA                          128  TLS1    Native  RC4     SHA     RSA
15:     5  RC4-SHA                          128  TLS1.1  Native  RC4     SHA     RSA
16:     5  RC4-SHA                          128  TLS1.2  Native  RC4     SHA     RSA
17: 49172  ECDHE-RSA-AES256-CBC-SHA         256  TLS1    Native  AES     SHA     ECDHE_RSA
18: 49172  ECDHE-RSA-AES256-CBC-SHA         256  TLS1.1  Native  AES     SHA     ECDHE_RSA
19: 49172  ECDHE-RSA-AES256-CBC-SHA         256  TLS1.2  Native  AES     SHA     ECDHE_RSA
20: 49191  ECDHE-RSA-AES128-SHA256          128  TLS1.2  Native  AES     SHA256  ECDHE_RSA
21: 49171  ECDHE-RSA-AES128-CBC-SHA         128  TLS1    Native  AES     SHA     ECDHE_RSA
22: 49171  ECDHE-RSA-AES128-CBC-SHA         128  TLS1.1  Native  AES     SHA     ECDHE_RSA
23: 49171  ECDHE-RSA-AES128-CBC-SHA         128  TLS1.2  Native  AES     SHA     ECDHE_RSA
24: 49170  ECDHE-RSA-DES-CBC3-SHA           192  TLS1    Native  DES     SHA     ECDHE_RSA
25: 49170  ECDHE-RSA-DES-CBC3-SHA           192  TLS1.1  Native  DES     SHA     ECDHE_RSA
26: 49170  ECDHE-RSA-DES-CBC3-SHA           192  TLS1.2  Native  DES     SHA     ECDHE_RSA