F5 certificate not working for all ports.

I think the SSL error you show is probably client-related. Maybe try a different client and also manually add the Host header as appropriate. You don't have a default pool assigned to your virtual server and there is no else clause in the iRule in which case without the required Host header it will send a reset.

Maybe add more logging to your iRule and possibly other events like LB_FAILED and CLIENT_CONNECTED. You can also use the SSL events. This will show you more information for debugging and probably lead you right to the issue.