Enable/Disable ProxySSL in iRule

Alternatively if you want to switch SSL profiles to one with the options you need then use SSL::profile

when HTTP_REQUEST {
  set uri [HTTP::uri]
}

when SERVER_CONNECTED {
  if {$uri equals "/myapplication" } {
    SSL::profile serverssl_profile
  }
}

This will switch the SSL profile to the specified. This must occur before the serverside SSL negotiation has occurred or you will need to use SSL:renegotiate.