Enable Request Adapt for Specific uri's

You need an iRule which only enables the Request Adaptation when the URI matches the URI of file upload and disables it for all other URI otherwise all requests are going to go though ICAP, perhaps something like this:

when HTTP_REQUEST {
 if {([HTTP::method] eq "POST") && ([HTTP::uri] starts_with "/doc/upload/") } {
    ADAPT::enable true
 } else {
    ADAPT::enable false
 }
}