Distribute client request on the basis of the health monitor with the help of Irule.

Create two seperate pools for port 21 and 22. Lets say port 21 uses the pool ftp_pool and port 22 uses ssh_pool. Create seperate health monitors for each pool to use TCP monitor and respective ports. Remove default pool from the virtual server 10.10.10.10:0 and attach below irule.

when CLIENT_ACCEPTED {
  if {[TCP::local_port] == 21}  {
   pool ftp_pool
  } elseif {[TCP::local_port] == 22} {
  pool ssh_pool
 }
}

-Jinshu