Yes the communication is proper , I created a default route towards the exiting vlan for VIP , the traffic was leaving but what I found since ISE and Switch lies in the same segment , its difficult to implement the configuration , also in case of Radius vip the COA assigned by ISE for authentication needs to be passed to the switch so somehow there should be a direct communication from Source to Pool member. I am just wondering if Auto Last Hop affects the traffic here , since its a VM with single interface enabled , the traffic exiting from f5 towards ISE never makes back to f5.