choosing self-IPs for iQuery communication

Lookup GTM DataCenter. It will lead you how to setup different "groups" and configure the LTM's under each "location"

--When you configure host in a Datacenter, you will specify two IP's, monitored by big3d. The GTM will know when one or the other LTM is down, but keep your WIPs UP. The IP's will be the non-floating Self IP of the IP/VLAN your VIPs communicate.

You also will want to research Topology.--Based on a users location, Topology will look at the user's IP and send them to that VS.