Can I keep persistance using Single Signon Cookie?

A better way to do this is to use cookie hash persistence. To enable, it, create a persistence profile of mode cookie and specify a cookie mode of hash with a cookie name, hash offset, and hash length. If you do not know the length, you can use zero and the full value of the cookie will be used. This approach does not require an iRule. As its name suggests, the session persistence is based on a hash of the cookie value.