Azure App Services and routing,protecting with F5

Is it possible for Azure F5 LTM module to load balance or route traffic to Azure Web apps? I have web app http://xyz.azurewebapp.net and I want to route this traffic form Azure F5 LTM module www.mycompany.com. The reason for routing through F5 is to secure it and block unwanted url to be accessible by the public and also domain verification is not an option for us. 

Azure app gateway does this for us, want to see if F5 can do this. Any pointer is appreciated.