Advance Customization of Full Webtop :: BIGIP APM

yeah, there isn't a whole lot you can do. though you can take out that help and textbox fine, see sol:

http://support.f5.com/kb/en-us/solutions/public/13000/500/sol13593.html

and this other question

https://devcentral.f5.com/questions/apm-remove-the-home-button-search-field-part

but if you want to change the general style it probably means diving much deeper and exactly why do you want to?