Simple HTTP::uri rule doesn't work as expected

You are doing everything correctly and it should work. The value HTTP::uri does not contain any header values so odds are something else is amiss.

I would start by throwing in some logging

when HTTP_REQUEST {
 log local0. "Requested URI: [HTTP::uri]"
 if {[string tolower [HTTP::uri]] starts_with "/jsfeatured.php"} {
  log local0. "URI: [HTTP::uri] matched /jsfeatured.php"
  pool jsfeatured_pool_80
 } elseif {[string tolower [HTTP::uri]] starts_with "/js.php"} {
  log local0. "URI: [HTTP::uri] matched /js.php"
  pool jobsearch_pool_80
 } else {
  log local0. "URI: [HTTP::uri] not matched"
 }
}

Then look in the /var/log/ltm file and you'll see the output of the log messages. In most cases, watching the logic flow can help diagnosing these problems.

Stupid question, but could the jsfeatured_pool_80 be the default pool for the virtual? If so, not overriding in the iRule would route there.

-Joe