Problem with lets encrypt and redirect after update

General: It is not a good idea to add two iRules without explicit priorities and without response guards.

I assume this is your problem: https://my.f5.com/manage/s/article/K000137608

I would merge the two iRules.

when HTTP_REQUEST {
    if { [HTTP::path] starts_with "/.well-known/acme-challenge/" } {
        set token [lindex [split [HTTP::path] "/"] end]
        set response [class match -value -- $token equals acme_responses]
        if { "$response" == "" } {
            log local0. "Responding with 404 to ACME challenge $token"
            HTTP::respond 404 content "Challenge-response token not found."
        } else {
            log local0. "Responding to ACME challenge $token with response $response"
            HTTP::respond 200 content "$response" "Content-Type" "text/plain; charset=utf-8"
        }
    } else {
        HTTP::redirect https://[getfield [HTTP::host] ":" 1][HTTP::uri]
    }
}