Please help in creating a content switching irule

Give it a shot.

when HTTP_REQUEST {

  if {[HTTP::host] == "xyz.abc.com"} {
    switch -glob [HTTP::uri] {
      "/providerportal1/*" -
      "/Resources/*" -
      "/provider_get/*" -
      "/exadmin/*" {
        pool pool1
      }
      "/portal/*" {
        pool pool2
      }
    }
  }

}