layer4-payload UUID persistence

You will have to use universal persistence and write an irule that will parse the payload for identifier you are looking for. Looks like your payloads contain UUID= somewhere and your ACE uses it value to persist. Do you know where that is in the payload? Is it always in the first x amount of bytes?

You can try this irule:

when HTTP_REQUEST {
     extract UUID parameter value from URI
    set uuid [URI::query [HTTP::uri] UUID]
    if { !($uuid equals "") } {
    persist uie $uuid
  }
}
when LB_SELECTED {
     add a persistence record when pool member is selected.
    if { !($uuid equals "") } {
        persist add uie $uuid
    }
}