Issue seeing session cookie in subsequent requests after being inserted using irule.

You mentioned:

I see the cookies, TLTSID and TLTUID being inserted by the LTM on the response and being received by the client workstation. However, i do not see the TLTSID and TLTUID cookies being sent on subsequent GET requests from the client

which tells me that this is a client side issue. If the cookies are being sent to the browser, but the browser doesn't send them back, you can generally infer that there's probably either something wrong with the cookie, or some attribute of the cookie (path, domain, expiration, secure, httponly) that is causing the browser to not send it back. The domain attribute immediately stands out in your code. If you're setting a domain attribute in the cookie, and the browser isn't requesting something from that domain, it simply won't send back the cookie.