Is a Dedicated Interface, VLAN, and Self IP Required for a VIP in an F5 Configuration?

This is my setup: the VIP is in a separate subnet from the Self-IPs, the management interface, and the pool members. To handle this configuration, I have two VLANs and corresponding Self-IPs because the pool members are split across two different subnets.

We are not using HA in this setup; failover will be done manually for now to keep things simple.

Currently, the F5 Main is set to act as the active node. However, we are facing challenges with the VIP configuration. My question is: would it be better to create two pools, one for each subnet, or can I use a single pool with all four members (two from each subnet)?

Additionally, do I need to explicitly connect the VIP to the VLANs and Self-IPs to route traffic correctly? Should I also use SNAT to ensure proper communication between the pool members and clients?

Does this configuration work as described, or are there better recommendations for achieving this setup?