irule to enable http/2 acceleration

Hello,

I got some case, we have some virtual server with irules we want to enable http/2 for specific FQDN, but we don't want enable the http/2 profile on the virtual server, because it will impact all FQDN that handled by that virtual server.

it is possible to enable http/2 acceleration using irule? Or the only way to enable http/2 profile is using configuration utility only

Thanks