iRule for non http services

yes, irules is not limited to http
https://clouddocs.f5.com/api/irules/

however, from your irules it seems it is http based service though not on port 80.
http does not always use port 80
the virtual server needs to have http profile to have http realted irules works

instead of irules scripting, you can also use gui based traffic policy
https://techdocs.f5.com/en-us/bigip-15-1-0/big-ip-local-traffic-management-getting-started-with-policies/introducing-local-traffic-policies.html#GUID-A29C4871-6F8C-4230-8A8D-1F746120488E