irule Client Accept and HTTP request conflict ?

You can’t apply HTTP_REQUEST event irule to performance L4 virtual server. Standard mode is required.

Then if you change the mode, the CLIENT_ACCEPTED will first assign the pool. But no traffic will be sent to the server yet. Then when first request is received, if the host header matches the HTTP_REQUEST condition, the new pool assignment will be applied.

In the same client side tcp connection, you can change multiple times the pool assignment.