Interface between F5 and Cisco Catalyst 6500 gives errors

Odd, I don't see any LACP in the F5 output. You'd want to compare whatever method is used on the Catalyst with whatever you have configured on the F5. This from a Cisco article;

Overrun: Number of times the receiver hardware was unable to hand received data to a hardware buffer because the input rate exceeded the receiver’s ability to handle the data.

suggests the Cisco can't keep up. If it's a bundle why have you only shown us one link?

It might help if you could post the full interface output and configuration for both devices.