Integration of reverse proxy with Squid proxy

Hi!

Have you assigned a server ssl profile? Otherwise the request might use http to contact a https listener which could generate the error you describe.

Just out of curiosity, if you want to offload the squid server by using the F5, why do you still send the traffic to https instead of http?

As for the iRule, try something like this:

when HTTP_REQUEST {

    set host [string tolower [HTTP::uri]]

    The condition below can be omitted in case you want to rewrite all requests
    if { $host eq "abc.123.com" } {
        [HTTP::host] "xyz.456.com"
    }

} 

Good luck!

/Patrik