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HTTP 1.1 concurrent to HTTP 1.1 Pipelining
I'd avoid HTTP pipelining if possible. It doesn't offer benefit over normal keep-alive in the context of reducing SSL handshakes. It's also somewhat rare to see in actual use, which increases the risk of incompatibilities between the client and server and the risk of vulnerabilities like request smuggling. Also it looks like Chromium doesn't support it.
Reducing SSL handshakes is the main purpose of BIG-IP's "OneConnect" profile, it allows re-use of already open TCP channels.
Here's a good post that discusses it:
https://wtit.com/blog/2019/09/24/understanding-f5-oneconnect/
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