F5 APM (failed to initialize local tunnel server)

I've come across this issue in various disguises and had different ways of resolving it. It's a very random issue that seems to only affect certain people for no reason.

Here are the few ways we've come across that work (bearing in mind we're on a corporate network with multiple GPOs or restrictions in place)

1. Rebuild laptop ..... drastic measure but for some installs the laptop work better on a clean laptop than trying to use the debug tool to do a full removal of the plugins.
2. Change tunnelserver.exe to run in windows 7 compatibility mode (unhide the directory in windows 8 first).
3. Remove Malwarebytes or other security software except anti-virus. Mayware bytes prevents the tunnel being established.
4. Full admin uninstall / reinstall by someone with Administrator rights (randomly works !!!).
5. Making sure any network proxies are allowing both .exe and .cab files through to your browser
6. Making sure no WAN Accelerators are manipulating the traffic when trying to setup a tunnel (DTLS especially)

Then after all this ... there's still the odd person we just simply couldn't help :)