Yes, the Infoblox Load Balancer Manager communicates with the entire network of Global Traffic Managers via the iControl API. The actual communication is made via the Grid Master or the designated synch member of the Infoblox Grid. Changes made centrally are pushed to the entire network automatically without requiring the network administrator to log onto each F5 GTM appliance. For more information on the joint solution, please see the link above. You also can access the Infoblox forum that corresponds to this one – they are offering a free t-shirt for all DevCentral members who join the Infoblox bloxHub Traffic Manager Integration forum [http://www.infoblox.com/community/content/traffic-management-integration] by August 15, 2012.
PS: I work in product marketing at Infoblox and try to answer forum questions as much as possible.