Enterprise Manager (EM) HA options with 2 data centers

I am currently looking at a similar solution.

 

-2 data centers (essentially a tunnel between the boxes)

 

-Statistics on an external MySQL 5.1 box (New in 2.3)

 

-Configurations backed up for all devices on both EMs

 

 

This seems like a sound method for highly available backups.

 

 

I have the same question lingering in my mind though:

 

-Are there any obvious caveats to having a single (GTM/LTM) device being connected to multiple EM devices?

 

 

Thanks,

 

--Kevin