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Design question - LTMs in DC1 and resources in DC2
This is not an uncommon setup. We have LTMs in a data center that have pool members that reside elsewhere across a WAN. Our virtual servers use address space out of the local vlan (vlan 100 in your case) and the pool members (real servers) use whatever IP address they are assigned. Vlan number isn't significant in this case since the communications will be routed from the LTM to wherever the destination is, so vlan won't even be a consideration for the LTM from the server perspective.
You'll only need to ensure that you have an appropriate route defined to get to the pool members and it should work without issue.
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