Delivering Secure Application Services Anywhere with Nutanix Flow and F5 Distributed Cloud
Introduction F5 Application Delivery and Security Platform (ADSP) is the premier solution for converging high-performance delivery and security for every app and API across any environment. It provides a unified platform offering granular visibility, streamlined operations, and AI-driven insights — deployable anywhere and in any form factor. The F5 ADSP Partner Ecosystem brings together a broad range of partners to deliver customer value across the entire lifecycle. This includes cohesive solutions, cloud synergies, and access to expert services that help customers maximize outcomes while simplifying operations. In this article, we’ll explore the upcoming integration between Nutanix Flow and F5 Distributed Cloud, showcasing how F5 and Nutanix collaborate to deliver secure, resilient application services across hybrid and multi-cloud environments. Integration Overview At the heart of this integration is the capability to deploy a F5 Distributed Cloud Customer Edge (CE) inside a Nutanix Flow VPC, establish BGP peering with the Nutanix Flow BGP Gateway, and inject CE-advertised BGP routes into the VPC routing table. This architecture provides us complete control over application delivery and security within the VPC. We can selectively advertise HTTP load balancers (LBs) or VIPs to designated VPCs, ensuring secure and efficient connectivity. Additionally, the integration securely simplifies network segmentation across hybrid and multi-cloud environments. By leveraging F5 Distributed Cloud to segment and extend the network to remote locations, combined with Nutanix Flow Security for microsegmentation within VPCs, we deliver comprehensive end-to-end network security. This approach enforces a consistent security posture while simplifying segmentation across environments. In this article, we’ll focus on application delivery and security, and explore segmentation in the next article. Demo Walkthrough Let’s walk through a demo to see how this integration works. The goal of this demo is to enable secure application delivery for nutanix5.f5-demo.com within the Nutanix Flow Virtual Private Cloud (VPC) named dev3. Our demo environment, dev3, is a Nutanix Flow VPC with a F5 Distributed Cloud Customer Edge (CE) named jy-nutanix-overlay-dev3 deployed inside: *Note: CE is named jy-nutanix-overlay-dev3 in the F5 Distributed Cloud Console and xc-ce-dev3 in the Nutanix Prism Central. eBGP peering is ESTABLISHED between the CE and the Nutanix Flow BGP Gateway: On the F5 Distributed Cloud Console, we created an HTTP Load Balancer named jy-nutanix-internal-5 serving the FQDN nutanix5.f5-demo.com. This load balancer distributes workloads across hybrid multicloud environments and is protected by a WAF policy named nutanix-demo: We advertised this HTTP Load Balancer with a Virtual IP (VIP) 10.10.111.175 to the CE jy-nutanix-overlay-dev3 deployed inside Nutanix Flow VPC dev3: The CE then advertised the VIP route to its peer via BGP – the Nutanix Flow BGP Gateway: The Nutanix Flow BGP Gateway received the VIP route and installed it in the VPC routing table: Finally, the VMs in dev3 can securely access nutanix5.f5-demo.com while continuing to use the VPC logical router as their default gateway: F5 Distributed Cloud Console observability provides deep visibility into applications and security events. For example, it offers comprehensive dashboards and metrics to monitor the performance and health of applications served through HTTP load balancers. These include detailed insights into traffic patterns, latency, HTTP error rates, and the status of backend services: Furthermore, the built-in AI assistant provides real-time visibility and actionable guidance on security incidents, improving situational awareness and supporting informed decision-making. This capability enables rapid threat detection and response, helping maintain a strong and resilient security posture: Conclusion The integration demonstrates how F5 Distributed Cloud and Nutanix Flow collaborate to deliver secure, resilient application services across hybrid and multi-cloud environments. Together, F5 and Nutanix enable organizations to scale with confidence, optimize application performance, and maintain robust security—empowering businesses to achieve greater agility and resilience across any environment. This integration is coming soon in CY2026. If you’re interested in early access, please contact your F5 representative. Related URLs Simplifying and Securing Network Segmentation with F5 Distributed Cloud and Nutanix Flow | DevCentral F5 Distributed Cloud - https://www.f5.com/products/distributed-cloud-services Nutanix Flow Virtual Networking - https://www.nutanix.com/products/flow/networking
Simplifying and Securing Network Segmentation with F5 Distributed Cloud and Nutanix Flow
Introduction Enterprises often separate environments—such as development and production—to improve efficiency, reduce risk, and maintain compliance. A critical enabler of this separation is network segmentation, which isolates networks into smaller, secured segments—strengthening security, optimizing performance, and supporting regulatory standards. In this article, we explore the integration between Nutanix Flow and F5 Distributed Cloud, showcasing how F5 and Nutanix collaborate to simplify and secure network segmentation across diverse environments—on-premises, remote, and hybrid multicloud. Integration Overview At the heart of this integration is the capability to deploy a F5 Distributed Cloud Customer Edge (CE) inside a Nutanix Flow VPC, establish BGP peering with the Nutanix Flow BGP Gateway, and inject CE-advertised BGP routes into the VPC routing table. This architecture provides full control over application delivery and security within the VPC. It enables selective advertisement of HTTP load balancers (LBs) or VIPs to designated VPCs, ensuring secure and efficient connectivity. By leveraging F5 Distributed Cloud to segment and extend networks to remote location—whether on-premises or in the public cloud—combined with Nutanix Flow for microsegmentation within VPCs, enterprises achieve comprehensive end-to-end security. This approach enforces a consistent security posture while reducing complexity across diverse infrastructures. In our previous article (click here) , we explored application delivery and security. Here, we focus on network segmentation and how this integration simplifies connectivity across environments. Demo Walkthrough The demo consists of two parts: Extending a local network segment from a Nutanix Flow VPC to a remote site using F5 Distributed Cloud. Applying microsegmentation within the network segment using Nutanix Flow Security Next-Gen. San Jose (SJ) serves as our local site, and the demo environment dev3 is a Nutanix Flow VPC with an F5 Distributed Cloud Customer Edge (CE) deployed inside: *Note: The SJ CE is named jy-nutanix-overlay-dev3 in the F5 Distributed Cloud Console and xc-ce-dev3 in the Nutanix Prism Central. On the F5 Distributed Cloud Console, we created a network segment named jy-nutanix-sjc-nyc-segment and we assigned it specifically to the subnet 192.170.84.0/24: eBGP peering is ESTABLISHED between the CE and the Nutanix Flow BGP Gateway in this segment: At the remote site in NYC, a CE named jy-nutanix-nyc is deployed with a local subnet of 192.168.60.0/24: To extend jy-nutanix-sjc-nyc-segment from SJ to NYC, simply assign the segment jy-nutanix-sjc-nyc-segment to the NYC CE local subnet 192.168.60.0/24 in the F5 Distributed Cloud Console: Effortlessly and in no time, the segment jy-nutanix-sjc-nyc-segment is now extended across environments from SJ to NYC: Checking the CE routing table, we can see that the local routes originated from the CEs are being exchanged among them: At the local site SJ, the SJ CE jy-nutanix-overlay-dev3 advertises the remote route originating from the NYC CE jy-nutanix-nyc to the Nutanix Flow BGP Gateway via BGP, and installs the route in the dev3 routing table: SJ VMs can now reach NYC VMs and vice versa, while continuing to use their Nutanix Flow VPC logical router as the default gateway: To enforce granular security within the segment, Nutanix Flow Security Next-Gen provides microsegmentation. Together, F5 Distributed Cloud and Nutanix Flow Security Next-Gen deliver a cohesive solution: F5 Distributed cloud seamlessly extends network segments across environments, while Nutanix Flow Security Next-Gen ensures fine-grained security controls within those segments: Our demo extends a network segment between two data centers, but the same approach can also be applied between on-premises and public cloud environments—delivering flexibility across hybrid multicloud environments. Conclusion F5 Distributed Cloud simplifies network segmentation across hybrid and multi-cloud environments, making it both secure and effortless. By seamlessly extending network segments across any environment, F5 removes the complexity traditionally associated with connecting diverse infrastructures. Combined with Nutanix Flow Security Next-Gen for microsegmentation within each segment, this integration delivers end-to-end protection and consistent policy enforcement. Together, F5 and Nutanix help enterprises reduce operational overhead, maintain compliance, and strengthen security—while enabling agility and scalability across all environments. This integration is coming soon in CY2026. If you’re interested in early access, please contact your F5 representative. Related URLs Delivering Secure Application Services Anywhere with Nutanix Flow and F5 Distributed Cloud | DevCentral F5 Distributed Cloud - https://www.f5.com/products/distributed-cloud-services Nutanix Flow Network Security - https://www.nutanix.com/products/flow
