Delivering Secure Application Services Anywhere with Nutanix Flow and F5 Distributed Cloud
Introduction F5 Application Delivery and Security Platform (ADSP) is the premier solution for converging high-performance delivery and security for every app and API across any environment. It provides a unified platform offering granular visibility, streamlined operations, and AI-driven insights — deployable anywhere and in any form factor. The F5 ADSP Partner Ecosystem brings together a broad range of partners to deliver customer value across the entire lifecycle. This includes cohesive solutions, cloud synergies, and access to expert services that help customers maximize outcomes while simplifying operations. In this article, we’ll explore the upcoming integration between Nutanix Flow and F5 Distributed Cloud, showcasing how F5 and Nutanix collaborate to deliver secure, resilient application services across hybrid and multi-cloud environments. Integration Overview At the heart of this integration is the capability to deploy a F5 Distributed Cloud Customer Edge (CE) inside a Nutanix Flow VPC, establish BGP peering with the Nutanix Flow BGP Gateway, and inject CE-advertised BGP routes into the VPC routing table. This architecture provides us complete control over application delivery and security within the VPC. We can selectively advertise HTTP load balancers (LBs) or VIPs to designated VPCs, ensuring secure and efficient connectivity. Additionally, the integration securely simplifies network segmentation across hybrid and multi-cloud environments. By leveraging F5 Distributed Cloud to segment and extend the network to remote locations, combined with Nutanix Flow Security for microsegmentation within VPCs, we deliver comprehensive end-to-end network security. This approach enforces a consistent security posture while simplifying segmentation across environments. In this article, we’ll focus on application delivery and security, and explore segmentation in the next article. Demo Walkthrough Let’s walk through a demo to see how this integration works. The goal of this demo is to enable secure application delivery for nutanix5.f5-demo.com within the Nutanix Flow Virtual Private Cloud (VPC) named dev3. Our demo environment, dev3, is a Nutanix Flow VPC with a F5 Distributed Cloud Customer Edge (CE) named jy-nutanix-overlay-dev3 deployed inside: *Note: CE is named jy-nutanix-overlay-dev3 in the F5 Distributed Cloud Console and xc-ce-dev3 in the Nutanix Prism Central. eBGP peering is ESTABLISHED between the CE and the Nutanix Flow BGP Gateway: On the F5 Distributed Cloud Console, we created an HTTP Load Balancer named jy-nutanix-internal-5 serving the FQDN nutanix5.f5-demo.com. This load balancer distributes workloads across hybrid multicloud environments and is protected by a WAF policy named nutanix-demo: We advertised this HTTP Load Balancer with a Virtual IP (VIP) 10.10.111.175 to the CE jy-nutanix-overlay-dev3 deployed inside Nutanix Flow VPC dev3: The CE then advertised the VIP route to its peer via BGP – the Nutanix Flow BGP Gateway: The Nutanix Flow BGP Gateway received the VIP route and installed it in the VPC routing table: Finally, the VMs in dev3 can securely access nutanix5.f5-demo.com while continuing to use the VPC logical router as their default gateway: F5 Distributed Cloud Console observability provides deep visibility into applications and security events. For example, it offers comprehensive dashboards and metrics to monitor the performance and health of applications served through HTTP load balancers. These include detailed insights into traffic patterns, latency, HTTP error rates, and the status of backend services: Furthermore, the built-in AI assistant provides real-time visibility and actionable guidance on security incidents, improving situational awareness and supporting informed decision-making. This capability enables rapid threat detection and response, helping maintain a strong and resilient security posture: Conclusion The integration demonstrates how F5 Distributed Cloud and Nutanix Flow collaborate to deliver secure, resilient application services across hybrid and multi-cloud environments. Together, F5 and Nutanix enable organizations to scale with confidence, optimize application performance, and maintain robust security—empowering businesses to achieve greater agility and resilience across any environment. This integration is coming soon in CY2026. If you’re interested in early access, please contact your F5 representative. Reference URLs https://www.f5.com/products/distributed-cloud-services https://www.nutanix.com/products/flow/networking
