Need help on i-rule to specific uri path

The insecure HTTPS message is very unlikely to have been caused by your iRule - most likely it is because the server IP/name you are going to in order to reach the Virtual Server does not match the CN in the SSL certificate returned by the pool member.

Regarding the iRule; I strongly suggest using [HTTP::uri -normalized] to ensure that your iRule cannot be bypassed by encoding slashes or other bypasses (e.g. //, //./, %2F etc) (everyone should be doing this, really!). Other than that, Sanjay's rule above should be more efficient.