Long list of redirections on a Data Group that not always works

Note that if more than one HTTP request is received on the same connection, only the first will trigger your iRule because you unilaterally disable the HTTP_REQUEST event at the end of your iRule, regardless of whether any redirection occurred or not. Therefore, if a second HTTP request comes in on the same connection, your iRule will not trigger. Unless there is a specific reason to disable the HTTP_REQUEST event, you should probably remove the event disable command.